Description

Our Hollow Fiber Systems & ATF (Alternating Tangential Flow) solutions are engineered for efficient cell retention, continuous perfusion, and high-density cell culture processes. Designed to deliver consistent performance, they enable enhanced productivity while maintaining optimal cell viability and product quality.

The hollow fiber membranes provide high surface area, excellent permeability, and low shear stress, making them ideal for long-term perfusion and sensitive biological applications. ATF technology ensures gentle yet effective filtration, supporting continuous media exchange and waste removal without interrupting cell growth.

Widely used in biopharmaceutical manufacturing, monoclonal antibody production, vaccine development, and cell & gene therapy, our Hollow Fiber & ATF systems support smooth scalability from laboratory research to commercial production, meeting demanding process and regulatory requirements.

S.No	Applications	Effective Length	Batch Size	Ultra-Filtration (MWCO)	Micro-Filtration	Lumen ID	Sterilization	Membrane
Hollow Fibers
1	Purification, concentration and diafiltration of vaccine	30cm 60cm 110cm	100ml – 1500L	3kD – 750kD	0.1μm – 0.65μm	0.5mm / 1.0mm	Autoclavable (In this we have available only 750 kD & 0.2 μm)	PES
2	Purification, concentration and diafiltration of viral vector
3	Clarification of cells and bacterial in fermentation broth
4	Recycling and washing of cells and bacteria
5	Concentration and diafiltration of protein
*Note : For more detailed specifications and technical assistance, kindly contact our technical team.**

S.No	Applications	Accessories	Resolution	Culture Stage	Product Model
ATF
1	Perfusion cell culture process, including • N-1 high cell density seed culturing • Medium exchanging and target product harvesting in dynamic/continuous perfusion cell culturing • Medium exchanging in concentrated fed-batch cell culturing • Cell lysis clarification and concentration	Available with different Diaphragms & Hollow fiber assemblies & Tubing Assemblies	0.2 μm 50 kd	N-1 N-1/N N	ATF2 ATF6 ATF10
2	Multiple fields of cell/ microbial culture including • Bio-pharmaceuticals such as antibody, vaccine and CGT. • Food industries such as culture meat and wine-making.		0.2 μm 50 kd	N-1 N-1/N N	ATF2 ATF6 ATF10
*Note : For more detailed specifications and technical assistance, kindly contact our technical team.**

Hollow Fibers & ATF

Description

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